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- ********************************************************************
- * Prokaryotic sulfate- and thiosulfate-binding proteins signatures *
- ********************************************************************
-
- Sulfate-binding protein (gene sbp or sbpA) and thiosulfate-binding protein
- (gene cysP) are two structurally related periplasmic bacterial proteins which
- specifically bind sulfate and thiosulfate and are involved in the transport
- systems for these nutrients [1,2].
-
- As signature patterns for these proteins we selected two conserved regions;
- one located in the N-terminal region and the other in the central part of
- these proteins. The second pattern includes two adjacent amino acids (Ser-Gly)
- that, in sbp, are known to be essential for sulfate binding [3].
-
- -Consensus pattern: K-x-[NQEK]-[GT]-G-[DQ]-x-[LIVM]-x(3)-Q-S
- -Sequences known to belong to this class detected by the pattern: ALL.
- -Other sequence(s) detected in SWISS-PROT: NONE.
-
- -Consensus pattern: N-P-K-[ST]-S-G-x-A-R
- -Sequences known to belong to this class detected by the pattern: ALL.
- -Other sequence(s) detected in SWISS-PROT: NONE.
-
- -Last update: October 1993 / Patterns and text revised.
-
- [ 1] Hryniewicz M., Sirko A., Palucha A., Boeck A., Hulanicka D.
- J. Bacteriol. 172:3358-3366(1990).
- [ 2] Laudenbach D.E., Grossman A.R.
- J. Bacteriol. 173:2739-2750(1991).
- [ 3] Pflugrath J.W., Quiocho F.A.
- J. Mol. Biol. 200:163-180(1988).
-